![]() ![]() ![]() 3 An estimated 90% of MIs are the result of an acute thrombus that obstructs an atherosclerotic coronary artery. 2 The majority of MIs are the result of coronary artery disease. 1 MI typically results from an imbalance between oxygen supply and demand that is most often caused by plaque rupture with thrombus formation in an epicardial coronary artery, leading to an acute reduction of blood supply to a portion of the myocardium. 1,2 MIs are also associated with significant short- and long-term mortality and morbidity. Myocardial infarction (MI)-the irreversible necrosis of the cardiac muscle secondary to prolonged ischemia-is a leading cause of cardiovascular disease morbidity and mortality and is a frequent cause of hospital admissions in the United States. The pharmacist’s role in post-MI recovery and recurrence prevention includes medication education and helping patients maintain adherence to pharmacologic and nonpharmacologic treatment. Post-MI therapy and secondary prevention of MI involve the use of medication therapy and lifestyle modifications. Recurring MIs may put patients at risk for reduced quality of life, heart failure, and death. Recovery from an MI can take a physical and emotional toll on the affected patient and loved ones. The estimated annual incidences of new and recurrent MI events are 550,000 and 200,000, respectively. ABSTRACT: Myocardial infarction (MI) is defined as the irreversible necrosis of the cardiac muscle secondary to prolonged ischemia. ![]()
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